The INVOCELL Intravaginal Culture System (also referred to as the INVOCELL Culture System or the Vaginal Incubation System) consists of the INVOCELL Culture Device and the INVOCELL Retention Device.1
The INVOCELL Culture Device uses a woman’s body as an incubator to support fertilization and embryo development. The patient undergoes a mild ovarian stimulation and monitoring cycle. Once the eggs are retrieved and sperm is collected, they are placed into the INVOCELL Culture Device. The Culture device is then placed within the Retention device, which is then immediately positioned in the vagina to allow for fertilization and incubation to take place. Upon completion of the incubation period, the device is removed, allowing for the transfer or storage of embryos. For details regarding the INVOCELL procedure, please refer to the Instructions for Use.
In order to receive FDA clearance, 2 clinical studies were conducted. These studies provided data to support FDA clearance.
In 2015, the INVOCELL IVC System received clearance from the US Food and Drug Administration as the first IVC System.
INVOCELL is the first and only FDA-cleared IVC System.
A semen sample with normal semen parameters is required.
Yes, the INVOCELL IVC System may be an option for same-sex couples, similar to other ART.
The INVOCELL IVC System is a novel treatment option for individuals considering ART.
Similar to traditional IVF, eggs are retrieved in preparation for an INVOCELL procedure while, for IUI, the eggs remain within the body.
Please see Clinic Locations for a list of fertility clinics in the United States that currently offer the INVOCELL IVC System. Ferring is
in active conversations with additional healthcare providers and fertility clinics to increase accessibility of INVOCELL. We expect the
number of fertility clinics offering the INVOCELL IVC System to expand by leveraging Ferring’s resources, knowledge, and scale.
While a primary care physician or gynecologist may be able to begin the process of evaluation, and even prescribe basic treatments,
patients will need to see a fertility specialist for beyond basic testing and treatment.
Ferring is committed to helping people build families and live better lives. As a leader in reproductive medicine and women’s health,
the INVOCELL IVC System aligns with our mission of expanding fertility treatment options to couples navigating infertility.